For individuals seeking effective weight loss without undergoing surgery, 2025 offers a range of clinically proven, non-surgical options. These treatments — ranging from advanced endoscopic procedures to prescription medications and customized medical weight loss programs — are designed to help patients achieve meaningful, sustainable results with less risk and minimal downtime.
Below, we outline five of the top non-surgical weight loss solutions available this year.
What Is Non-Surgical Weight Loss?
Non-surgical weight loss includes medical interventions that promote weight reduction without the need for traditional bariatric surgery. These methods can include prescription medications, minimally invasive procedures, and comprehensive lifestyle programs overseen by healthcare professionals. They are generally safer than surgery, require little to no downtime, and are often more accessible in terms of cost and recovery.
Why Consider a Non-Surgical Approach?
- Lower risk compared to bariatric surgery
- Minimal recovery time
- Convenient, outpatient procedures
- Affordable options for a range of budgets
- Evidence-based results under medical supervision
Who Is a Candidate for Non-Surgical Weight Loss?
Many of these treatments are appropriate for individuals with a BMI between 30 and 40, though some may be eligible with a BMI of 27 or higher if weight-related conditions such as Type 2 diabetes, hypertension, or sleep apnea are present.
If you’ve struggled with weight loss through diet and exercise alone, non-surgical treatments may offer the clinical support and structure you need to succeed.
2025’s Top 5 Non-Surgical Weight Loss Treatments
1. Endoscopic Sleeve Gastroplasty (ESG)
How It Works:
ESG is a minimally-invasive, incision-free procedure that reduces the size of the stomach using sutures placed through an endoscope. This results in reduced food intake and earlier satiety. An endoscope is a thin, flexible tool with a camera that is inserted through the mouth and down the esophagus. For patient comfort and safety, this is performed under general anesthesia.
Key Benefits:
- Average total body weight loss of 15–20% within 12 months
- Outpatient procedure with rapid recovery
- No incisions, scars, or permanent alterations
- Reversible and repeatable if necessary
Ideal Candidates:
Adults with a BMI between 30 and 40 who have not achieved adequate results with diet and exercise alone may benefit from ESG.
2. Prescription Weight Loss Medications
Medications Offered at Weight Loss and Wellness Center:
- Wegovy (injectable)
- Zepboud (injectable)
- Saxenda (injectable)
- Qsymia (oral medication)
- Contrave (oral medication)
- Orlistat (oral medication)
How They Work:
Depending on which type you choose, these medications work in slightly different ways. Qysmia and Contrave are both oral appetite suppressants, so they reduce your hunger and cravings to help you ingest fewer calories. Orlistat is an oral fat absorption inhibitor that prevents your body from absorbing fats, thereby reducing the number of calories you absorb.
Saxenda, Wegovy, and Zepbound are injectable medications known as GLP1-agonists. These drugs mimic a hormone that your body naturally produces to regulate your appetite and control your blood sugar.
Who Benefits:
- Adults with a BMI ≥30
- Adults with a BMI ≥27 with conditions such as diabetes or hypertension
Important Consideration:
These medications must be prescribed and monitored by a licensed medical provider due to potential side effects and contraindications. Remember — not every medication is suitable for every patient. Dr. Majid at Weight Loss and Wellness Center is well-versed in the best applications for each of these medications to help her patients see the best possible results.
3. Physician-Supervised Medical Weight Loss Programs
Medical Weight Loss Program Components at Weight Loss and Wellness Center May Include:
- Personalized nutrition and exercise plans
- Behavioral health and habit coaching
- Metabolic testing and lab work
- Regular visits with physicians and registered dietitians
- Weight loss support groups
Why It’s Effective:
These programs offer a comprehensive, long-term approach to weight management. They are designed to address not only weight loss but also the root causes of obesity, including lifestyle factors and chronic disease risk. This is a wonderful opportunity for patients to get a truly personalized weight loss program.
4. Non-Surgical Body Contouring
Weight Loss and Wellness Center offers several types of non-invasive or minimally-invasive body contouring treatments. While these aren’t weight loss treatments, they do help eliminate excess fat. These treatments are more about losing inches than pounds. They are a fantastic way to target stubborn fat or excess skin after losing a significant amount of weight.
- CoolSculpting: Freezes and eliminates fat cells
- BodyTite: Melts fat and gently heats skin tissues to tighten and remodel them
- FaceTite: Same technology as BodyTite, but applied on the face or neck
- Morpheus8: Remodels skin tissue and stimulates collagen production through microneedling and radiofrequency energy
Who It’s For:
These treatments are ideal for individuals near their goal weight who wish to target localized fat deposits that are resistant to diet and exercise.
Note:
These procedures do not produce significant weight loss but can enhance body contour and complement a broader weight loss plan.
5. Customized Multi-Disciplinary Plans
Why Personalization Matters:
Effective weight loss is not one-size-fits-all. Working with a dedicated care team — including physicians, dietitians, fitness professionals, and behavioral coaches — can improve long-term outcomes.
At Weight Loss and Wellness Center, we take a holistic approach to weight loss. We’ll evaluate your health and discuss your goals to create a custom plan that may include several of our services together. After all, our goal is to help you not only lose weight, but improve your overall health for the long haul.
Program Benefits:
- Tailored goals and realistic timelines
- Flexibility in diet and activity based on lifestyle
- Ongoing support and accountability
- Integration with medical treatments if necessary
How to Choose the Right Option for You
Step 1: Evaluate Your Needs
Here are some things to consider when choosing a non-surgical weight loss treatment:
- Your current BMI and weight loss goals
- Any existing health conditions
- Your availability for appointments and follow-up
- Budget and insurance coverage
Step 2: Schedule a Medical Consultation
At your free consultation, our expert providers at Weight Loss and Wellness Center will:
- Review your medical history
- Recommend evidence-based options
- Make a plan for monitoring your progress and making necessary adjustment
Step 3: Combine Therapies if Appropriate
Many patients benefit from a blended approach — for example, GLP-1 medications paired with a structured weight loss program or ESG followed by ongoing lifestyle support.
But don’t worry — with Weight Loss and Wellness Center at your side, you won’t have to go it alone. Dr. Majid will help you determine the best combination for your health and your goals.
Begin Your Non-Surgical Weight Loss Journey Today
Whether you’re interested in ESG, considering weight loss medications, or exploring a personalized program, the team at Weight Loss and Wellness Center is here to help. Our board-certified providers offer evidence-based, compassionate care tailored to your needs.
📞 Call us at (973) 795-7955
🌐 Or visit www.weightlossandwellnesscenter.com to schedule your consultation.
Disclaimer: Individual results may vary. All treatments should be discussed with a licensed medical professional to determine whether they are appropriate for your individual health needs. This article is for informational purposes only and does not constitute medical advice.