What You Need To Know About Zepbound - Weightloss Injectible

Zepbound (tirzpatide), previously known as Mounjaro, was recently FDA-approved as a weight loss treatment. Currently, this injectible holds the potential to redefine the landscape of weight management, offering new hope for individuals grappling with chronic weight issues. Doctors recommend that a calorie-deficit diet and physical activity should accompany treatment. This drug is recommended for adults dealing with Obesity (BMI of 30 or greater) and those with weight-related medical problems. 


The Surmount trials, a study that included 2,539 adults with obesity and weight-related medical problems (excluding diabetes), tested the drug for weight loss and formed the basis for the approval. Accompanied by diet and exercise, the adults participating in the trial experienced substantial weight loss compared to those who took the placebo around the 72-week mark. 

Medical Uses

Developed by Eli Lilly, this innovative medication is currently the first and only of its kind. It has a unique mechanism of action that combines the benefits of two hormones—GLP-1 and GIP. These hormones play crucial roles in glucose and insulin regulation in the body. Studies have shown that the combination of these two hormones regulates appetite and lowers blood sugar to help promote weight loss. According to the 72-week study, The results showed that people who took tirzepatide lost more weight compared to those who took a placebo (a fake medicine). The higher the dose of tirzepatide, the more weight people lose. Participants who took the highest dose (15 mg) lost, on average, 48 pounds. Meanwhile, participants who took the placebo lost an average of 7 pounds.

Dosage Information

This medication should be taken as directed by your doctor. Zepbound comes in three dosages: 5mg, 10mg, and 15 mg. Zepbound is injected 1 time per week, any time of day. The drug should be injected under the skin of your stomach, thighs, or upper arms. Make sure you change the injection site every time. It’s essential to read all instructions included with the medication and ask questions from your healthcare provider.

Side Effects

Zepbound is a medicine for adults with obesity or excess weight who also have weight-related health issues. It helps with weight loss with a low-calorie diet and more physical activity. However, it contains tirzepatide and should not be used with anything containing tirzepatide or GLP-1 receptor medications. 

Zepbound may not be safe with other prescription, over-the-counter, or herbal weight loss products. It is not known if it’s safe for people who have had pancreatitis or for those under 18.

Common side effects include nausea, diarrhea, vomiting, constipation, indigestion, injection site reactions, belching, tiredness, hair loss, and heartburn. If you experience any side effects, talk to your healthcare provider.


There are warnings about possible thyroid tumours, and if you notice symptoms like neck swelling or trouble swallowing, tell your healthcare provider. Don’t use Zepbound if you or your family have a type of thyroid cancer or if you have a specific syndrome such as Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) or medullary thyroid carcinoma MTC. 


The medication may cause:

  • Severe stomach problems
  • Kidney issues
  • Gallbladder problems
  • Inflammation of the pancreas.

Severe allergic reactions, low blood sugar, changes in vision, and thoughts of suicide are also possible



Before using Zepbound for the first time:


  1. Ensure that your healthcare provider guides its proper usage.

  2. Inform your healthcare provider if you are currently using medications for diabetes, such as insulin or sulfonylureas, as they may elevate the risk of low blood sugar.

  3. If you are taking oral birth control pills, consult with your healthcare provider before initiating Zepbound. It’s important to note that the effectiveness of birth control pills may be reduced while using Zepbound. 


Your healthcare provider might recommend an alternative form of birth control for four weeks after starting Zepbound and for an additional four weeks following any dosage increases.


Most people struggle with losing weight and keeping it off, but your brain could be sabotaging your efforts and working against you. To find out if Zepbound would be an effective weight loss tool for you, simply contact our helpful team for more information.